This test is used to measure serum levels of leucine aminopeptidase (LAP), an isoenzyme of alkaline phosphatase (ALP) that is widely distributed in body tissues. The greatest concentrations appear in the hepatobiliary tissues, pancreas, and small intestine. Serum levels of LAP parallel serum ALP levels in hepatic disease.
Procedure and posttest care
Normal values are 80 to 200 U/ml in men and 75 to 185 U/ml in women
Elevated levels can occur in biliary obstruction, tumors, strictures, and atrelin; advanced pregnancy; and therapy with drugs containing estrogen or progesterone.
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